Discovery of tetrahydro γ-carboline based novel glucose uptake agent for the treatment of diabetes and Alzheimer's diseases

• Main Authors: Voggu, Ramakrishna, Balakrishnan, Durga Devi, Shukla, Priyanka, Puli, Venkat Swamy, Damerla, V. Surendra Babu, Rajan, Sreekanth, Chidara, Sridhar, Mogili, Padma, Pasunooti, Kalyan Kumar, Gupta, Sarika
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Anti-diabetic; Anti-Alzheimer
• Online Access: https://hdl.handle.net/10356/181354
• Institution: Nanyang Technological University

The emergence of diabetes mellitus (DM), one of the prevalent metabolic disorders, has increased at alarming rates around the globe in the past few decades. The early discovery of insulin paved the way for the broadened non-invasive anti-hyperglycemic drug therapies to manage and treat diabetes. Rec...