An "AND" logic gate-based supramolecular therapeutic nanoplatform for combatting drug-resistant non-small cell lung cancer

• Main Authors: Huang, Qili, Ding, Chendi, Wang, Wenyan, Yang, Li, Wu, Yinglong, Zeng, Wenfeng, Li, Zimu, Shi, Zhaoqing, Mei, Lin, Zeng, Xiaowei, Zhao, Yanli, Chen, Hongzhong
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Drug-resistance; Drug delivery system
• Online Access: https://hdl.handle.net/10356/181371
• Institution: Nanyang Technological University

Despite targeted therapies like epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), non-small cell lung cancer (NSCLC) remains a clinical challenge due to drug resistance hampering their efficacy. Here, we designed an "AND" logic gate-based supramolecular therapeutic p...