COVID-19 vaccination before or during pregnancy results in high, sustained maternal neutralizing activity to SARS-CoV-2 wild-type and Delta/Omicron variants of concern, particularly following a booster dose or infection

• Main Authors: Mahyuddin, Aniza P., Swa, Hannah L. F., Weng, Ruifen, Zhang, Jingxian, Dhanaraj, Janice P., Sesurajan, Binny P., Rauff, Mary, Dashraath, Pradip, Kanneganti, Abhiram, Lee, Rachel, Wang, Lin-Fa, Young, Barnaby Edward, Tambyah, Paul A., Lye, David C., Chai, Louis Y. A., Yee, Sidney, Choolani, Mahesh, Mattar, Citra N. Z.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; SARS-CoV-2; Pregnancy
• Online Access: https://hdl.handle.net/10356/181464
• Institution: Nanyang Technological University

Objectives: To investigate multi-dose and timings of COVID-19 vaccines in preventing antenatal infection. Design: Prospective observational study investigating primary vaccinations, boosters, antenatal COVID-19 infections, neutralizing antibody (Nab) durability, and cross-reactivity to Delta and Omi...