Genomic insights into idiopathic granulomatous mastitis through whole-exome sequencing: a case report of eight patients

• Main Authors: Ong, Seeu Si, Ho, Peh Joo, Khng, Alexis Jiaying, Tan, Benita Kiat Tee, Tan, Qing Ting, Tan, Ern Yu, Tan, Su-Ming, Putti, Thomas Choudary, Lim, Swee Ho, Tang, Serene Ee Ling, Li, Jingmei, Hartman, Mikael
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Breast abscess; Breast cancer
• Online Access: https://hdl.handle.net/10356/181554
• Institution: Nanyang Technological University

Idiopathic granulomatous mastitis (IGM) is a rare condition characterised by chronic inflammation and granuloma formation in the breast. The aetiology of IGM is unclear. By focusing on the protein-coding regions of the genome, where most disease-related mutations often occur, whole-exome sequencing...