Impact of esophageal motility on microbiome alterations in symptomatic gastroesophageal reflux disease patients with negative endoscopy: exploring the role of ineffective esophageal motility and contraction reserve

• Main Authors: Wong, Ming-Wun, Lo, I-Hsuan, Wu, Wei-Kai, Liu, Po-Yu, Yang, Yu-Tang, Chen, Chun-Yao, Wu, Ming-Shiang, Wong, Sunny Hei, Lei, Wei-Yi, Yi, Chih-Hsun, Liu, Tso-Tsai, Hung, Jui-Sheng, Liang, Shu-Wei, Gyawali, C. Prakash, Chen, Chien-Lin
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Contraction reserve; Esophageal motility disorders
• Online Access: https://hdl.handle.net/10356/181714
• Institution: Nanyang Technological University

Background/Aims: Ineffective esophageal motility (IEM) is common in patients with gastroesophageal reflux disease (GERD) and can be associated with poor esophageal contraction reserve on multiple rapid swallows. Alterations in the esophageal microbiome have been reported in GERD, but the relationsh...