High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo magnetic particle imaging

• Main Authors: Tay, Rong En, Lokamitra, P., Pang, Shun Toll, Low, Kay En, Tay, Hui Chien, Ho, Charmaine Min, Malleret, Benoit, Rötzschke, Olaf, Olivo, Malini, Tay, Zhi Wei
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; High efficiency magnetophoretic labelling; High throughput imaging
• Online Access: https://hdl.handle.net/10356/181737
• Institution: Nanyang Technological University

While adoptive cell therapies (ACT) have been successful as therapies for blood cancers, they have limited efficacy in treating solid tumours, where the tumour microenvironment excludes and suppresses adoptively transferred tumour-specific immune cells. A major obstacle to improving cell therapies f...