Novel functions of integrated stress response proteins on collided ribosomes
Ribosome stalling during translation can lead to ribosome collisions, providing a platform for the ribosome-associated quality control (RQC) and the integrated stress response (ISR) pathways. RQC dissociates stalled ribosomes through Hel2-mediated ubiquitylation of the small ribosome subunit protein...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2024
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| Online Access: | https://hdl.handle.net/10356/181788 |
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| Institution: | Nanyang Technological University |
| Language: | English |