Trifluoroacetic acid as a molecular probe for the dense phase in liquid-liquid phase-separating peptide systems

Although trifluoroacetic acid (TFA) is not typically considered a Hofmeister reagent, it has been demonstrated to modulate biocoacervation. We show that TFA can be employed to probe specific interactions in coacervating bioinspired peptide phenylalanine (Phe) 19F-labeled at a single site, altering i...

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Bibliographic Details
Main Authors: Lim, Jessica, Chin, Sze Yuet, Miserez, Ali, Xue, Kai, Pervushin, Konstantin
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2025
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Online Access:https://hdl.handle.net/10356/182198
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Institution: Nanyang Technological University
Language: English