Chronic cerebral hypoperfusion induces pathological venous remodelling via EPAS1 regulation

Cerebrovascular pathologies manifest in a zonation-dependent manner, though the impact of arteriovenous zonation on cognitive impairment remains unclear. We investigated the effects of cerebral hypoperfusion in mice through bilateral carotid artery stenosis, thereby recapitulating vascular dementia....

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Bibliographic Details
Main Author: Wazny, Vanessa Kristina
Other Authors: Christine Cheung
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2025
Subjects:
Online Access:https://hdl.handle.net/10356/182289
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Institution: Nanyang Technological University
Language: English
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