Exploring the membrane-active interactions of antimicrobial long-chain fatty acids using a supported lipid bilayer model for gram-positive bacterial membranes

• Main Authors: Shin, Sungmin, Yu, Jingyeong, Tae, Hyunhyuk, Zhao, Yilin, Jiang, Dongping, Qiao, Yuan, Kim, Wooseong, Cho, Nam-Joon
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2025
• Subjects: Engineering; Bacterial membranes; Supported lipid bilayer
• Online Access: https://hdl.handle.net/10356/182489
• Institution: Nanyang Technological University

The dynamic nature of bacterial lipid membranes significantly impacts the efficacy of antimicrobial therapies. However, traditional assay methods often fall short in replicating the complexity of these membranes, necessitating innovative approaches. Herein, we successfully fabricated model bacterial...