Predicting Asian glycemic responses in food using a physiologically-based pharmacokinetic-pharmacodynamic model

• Main Author: Koh, Hor Cheng
• Other Authors: Chen Wei Ning, William
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2025
• Subjects: Medicine, Health and Life Sciences; Glycemic response; Pharmacokinetics; Insulin; Glucose; Pharmacodynamics
• Online Access: https://hdl.handle.net/10356/182771
• Institution: Nanyang Technological University

Diabetes mellitus has become an ever-growing health concern especially in Singapore with a prevalence rate of 10.5%, markedly higher than the expected global average of 8.8%. Asians are naturally predisposed to greater degree of insulin secretion impairment and have a higher risk of developing predi...