Ionic hydrogen bond-assisted catalytic construction of nitrogen stereogenic center via formal desymmetrization of remote diols

• Main Authors: Luo, Zhongfu, Liao, Minghong, Li, Wei, Zhao, Sha, Tang, Kun, Zheng, Pengcheng, Chi, Robin Yonggui, Zhang, Xinglong, Wu, Xingxing
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2025
• Subjects: Chemistry; Nitrogen-stereogenicity; Organocatalysis
• Online Access: https://hdl.handle.net/10356/183582
• Institution: Nanyang Technological University

The control of noncarbon stereogenic centers is of profound importance owing to their enormous interest in bioactive compounds and chiral catalyst or ligand design for enantioselective synthesis. Despite various elegant approaches have been achieved for construction of S-, P-, Si- and B-stereocenter...