Applying ChIP and ChIA-PET to identify p300, CTCF and Lamin B binding sites in stem cells

• Main Author: Sheng, Jianpeng
• Other Authors: Wei, Chialin
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/18920
• Institution: Nanyang Technological University

Embryonic stem cells (ESCs) have the ability of self-renewal and differentiating into many different cell types, which makes it good choice as the cell source for stem cell therapy. And to exploit the potential of ESCs, two key pathways should be elucidated: the self-renewal process which will ampli...