Characteristics of Merkel Cell Polyomavirus T antigen oncoproteins.

• Main Author: Yu, Esther Dawen.
• Other Authors: Kristen Elizabeth Sadler
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/18936
• Institution: Nanyang Technological University

Merkel cell polyomavirus (MCV) is the first polyomavirus that can cause human cancer, and was discovered in January of 2008 (Huichen Feng, 2008). Its large T antigen shares structural and sequential similarities with SV40 T antigen and functional similarities with Human Papillomavirus (HPV) E7 pr...