Functional genomics analysis in human embryonic stem cells using RNA interference.

• Main Author: Wang, Yuwei.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/18994
• Institution: Nanyang Technological University

To fully understand self-renewal and pluripotency in hESCs, it is necessary to unravel genes that are crucial for these defined characteristics. Despite previous discovery of NANOG, OCT4 and SOX2 as key pluripotency associated genes, many genes and molecular mechanisms involved in pluripotency and s...