Neural cell adhesion molecule 180 participates in proliferation of melanoma cells through interaction with β-catenin.

• Main Author: Wong, Jack Jing Lin.
• Other Authors: Feng Zhiwei
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/19312
• Institution: Nanyang Technological University

Neural cell adhesion molecule (NCAM), a member of the immunoglobulin superfamily, is expressed not only in the neuronal system but also in various types of cancer including melanoma. Very often, its expression in cancer is highly dysregulated. NCAM performs diverse functions such as classical functi...