Understanding of disease severity of thalassemia.

• Main Author: Tao, Feng.
• Other Authors: Kai Tang
• Format: Theses and Dissertations
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/19318
• Institution: Nanyang Technological University

Thalassemia is an inherited autosomal recessive blood disease, which is caused by imbalanced expression of α and non-α hemoglobin subunits. Since quantitative relationship between globin chains is the major cause of disease, the severity of thalassemia disease is hypothesized correlated with quantit...