Functional genomics analysis in human embryonic stem cells using RNA interference.

• Main Author: Kuah, Jessica Si Jia.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/20264
• Institution: Nanyang Technological University

Human embryonic stem cells (hESCs) have the ability to proliferate indefinitely and remain undifferentiated due to their pluripotent characteristic. However, the mechanisms underlying their ability for self-renewal are still not well characterised. Key transcriptional regulators NANOG, OCT4 and SOX2...