Evoscan : a probabilistic framework for gene annotation using comparative genomics

• Main Author: Sangireddy Venugopal Reddy.
• Other Authors: Rajapakse, Jagath Chandana
• Format: Theses and Dissertations
• Published: 2008
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: http://hdl.handle.net/10356/2439
• Institution: Nanyang Technological University

Evoscan is based on a (pseudo higher-order) evolutionary hidden Markov model that integrates phylogenetic information into 'Genscan" code based on Twinscan. Its three major components consist of probabilistic models of both the DNA sequence, phylogenetic information of two or more closely...