Refractive index measurement of single living cell using biophotonic chip

Refractive index measurement of single living cell using biophotonic chip

This project combines microfluidic and micro-optical technologies to develop an integrated biophotonic chip for single cell analysis. More specifically the effective refractive index (RI) of cells is determined. The microfluidic system serves as a tool for single living cell manipulation, while the...

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Bibliographic Details
Main Authors: Liu, Ai Qun., Liang, Xiao Jun., Sun, Yi., Song, Wuzhou., Chin, Lip Ket.
Other Authors: School of Electrical and Electronic Engineering
Format: Research Report
Published: 2008
Subjects:
DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Online Access:http://hdl.handle.net/10356/2927
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Institution: Nanyang Technological University
Description
Summary:This project combines microfluidic and micro-optical technologies to develop an integrated biophotonic chip for single cell analysis. More specifically the effective refractive index (RI) of cells is determined. The microfluidic system serves as a tool for single living cell manipulation, while the micro-optical system serves as a sensor to measure the effective RI of a single living cell in real time. By using RI as an indicator, any slight changes inside the cells can be detected. Therefore the biophotonic chip has a series of potential applications in many disease diagnostic devices in the future.

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