Protein structure prediction using bidirectional neural networks
211 p.
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2010
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sg-ntu-dr.10356-357252023-03-04T00:40:29Z Protein structure prediction using bidirectional neural networks Chen, Jin Miao Narendra Shivaji Chaudhari School of Computer Engineering DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences 211 p. This thesis is focused on protein secondary structure (PSS) prediction which is one of the most important problems in bioinformatics. Most of existing prediction methods either use a sliding fixed-sized window centered on the residue of interest or train on single positions of the sequence to classify mutually independent secondary structures. They are unable to take into account long-range interactions between amino acids and strong correlations between secondary structure (SS) elements. In this thesis, we propose and develop three novel prediction models, namely bidirectional long short-term memory (BLSTM), bidirectional segmented-memory recurrent neural network (BSMRNN) and cascaded bidirectional recurrent neural network (Cascaded BRNN), which are all variants of bidirectional recurrent neural network (BRNN). DOCTOR OF PHILOSOPHY (SCE) 2010-04-23T01:30:55Z 2010-04-23T01:30:55Z 2007 2007 Thesis Chen, J. M. (2007). Protein structure prediction using bidirectional neural networks. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/35725 10.32657/10356/35725 application/pdf |
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Singapore Singapore |
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DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences |
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DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences Chen, Jin Miao Protein structure prediction using bidirectional neural networks |
| description |
211 p. |
| author2 |
Narendra Shivaji Chaudhari |
| author_facet |
Narendra Shivaji Chaudhari Chen, Jin Miao |
| format |
Theses and Dissertations |
| author |
Chen, Jin Miao |
| author_sort |
Chen, Jin Miao |
| title |
Protein structure prediction using bidirectional neural networks |
| title_short |
Protein structure prediction using bidirectional neural networks |
| title_full |
Protein structure prediction using bidirectional neural networks |
| title_fullStr |
Protein structure prediction using bidirectional neural networks |
| title_full_unstemmed |
Protein structure prediction using bidirectional neural networks |
| title_sort |
protein structure prediction using bidirectional neural networks |
| publishDate |
2010 |
| url |
https://hdl.handle.net/10356/35725 |
| _version_ |
1759858071463526400 |