Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma

58 p.

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Bibliographic Details
Main Author:	Chong, Ka Lan.
Other Authors:	Tan Nguan Soon
Format:	Theses and Dissertations
Published:	2010
Subjects:	DRNTU::Engineering::Bioengineering
Online Access:	http://hdl.handle.net/10356/36133
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Institution:	Nanyang Technological University

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spelling	sg-ntu-dr.10356-361332023-03-11T17:20:42Z Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma Chong, Ka Lan. Tan Nguan Soon School of Mechanical and Aerospace Engineering DRNTU::Engineering::Bioengineering 58 p. This study is to examine the expression of peroxisome proliferator-activated receptors (PPARs), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma. 20 archival paraffin-embedded biopsy specimens were selected from histopathology files of National Skin Centre, Singapore. These were 10 cases of invasive squamous cell carcinoma (SCC) and paired peritumoral normal skin specimens. Total RNA was extracted and reversed transcribed to cDNA. The expression of each gene, namely PPAR-a, PPAR-p/8, PPAR-y, HIF-la and FIAF was quantified by real-time PCR (QRT-PCR) and normalized to P-actin expression. Gene expression between tumor and peritumoral samples was analysed for statistical significance using Mann-Whitney test. Master of Science (Biomedical Engineering) 2010-04-23T02:29:54Z 2010-04-23T02:29:54Z 2007 2007 Thesis http://hdl.handle.net/10356/36133 application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
topic	DRNTU::Engineering::Bioengineering
spellingShingle	DRNTU::Engineering::Bioengineering Chong, Ka Lan. Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
description	58 p.
author2	Tan Nguan Soon
author_facet	Tan Nguan Soon Chong, Ka Lan.
format	Theses and Dissertations
author	Chong, Ka Lan.
author_sort	Chong, Ka Lan.
title	Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
title_short	Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
title_full	Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
title_fullStr	Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
title_full_unstemmed	Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma
title_sort	expression analysis of peroxisome proliferator-activated receptors (ppars), hypoxia-inducible factor (hif) and fasting-induced adipose factor (fiaf) in squamous cell carcinoma
publishDate	2010
url	http://hdl.handle.net/10356/36133
_version_	1761781659050442752

Expression analysis of peroxisome proliferator-activated receptors (PPARS), hypoxia-inducible factor (HIF) and fasting-induced adipose factor (FIAF) in squamous cell carcinoma

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