Optimizing parameters for the controlled release of drugs from biodegradable nanoparticles

• Main Author: Teo, Sheng Yuan.
• Other Authors: Loo Say Chye Joachim
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: http://hdl.handle.net/10356/36189
• Institution: Nanyang Technological University

Restenosis is a condition of re-narrowing of blood vessel that usually proceeds with angioplasty procedures. Paclitaxel (PCTX) is being administrated as an anti-proliferative therapy for the prevention of restenosis but poses adverse side effects due to high dosage used. Biodegradable polymeric nano...