Identification of RNA-Tis11b complexes in activated B cells.

• Main Author: Tang, Ngang Heok.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/38780
• Institution: Nanyang Technological University

RNA-binding proteins (RBPs) play important roles in regulating gene expression at post-transcriptional level. A type of RBPs, called 12-O-tetradecanoylphorbol-13-acetate (TPA) inducible sequence (TIS11) family members (Tis11, Tis11b and Tis11d), can bind to AU-rich elements (AREs) in 3’-untranslated...