Expression of angiogenic proteins in the retinal pigment epithelium of SPARC and HEVIN knockout mice.

• Main Author: Toh, Li Zhen.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/39400
• Institution: Nanyang Technological University

Introduction: Unregulated angiogenesis is associated with several ocular diseases. Vascular Endothelial Growth Factor (VEGF) family members are potent angiogenic stimulators and their elevated expressions are tightly associated with these diseases. VEGF activity is regulated, in part, by the matrice...