Insertional mutagenesis identifies Dph3 as a novel regulator of melanoma migration and invasion.

• Main Author: Yeo, Siok Ping.
• Other Authors: Feng Zhiwei
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/39405
• Institution: Nanyang Technological University

Malignant melanoma is the most deadly skin cancer in the world, yet there is no effective first-line treatment for metastatic melanoma. Thus, there is a need to look for new treatment options. Using insertional mutagenesis, we identified Rnf11, Dph3, Zmynd10 and Prdm5 as potential regulators of mela...