Understanding the role of LRRK2 in protein translation - implications for Parkinson's disease.

• Main Author: Cheng, Yue Xiang.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• Online Access: http://hdl.handle.net/10356/39552
• Institution: Nanyang Technological University

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder affecting millions of elderly worldwide. Although most cases of PD are idiopathic, a small proportion is caused by genetic mutations. Among these, mutations in Leucine Rich Repeat Kinase 2 (LRRK2) have been shown to be the most pre...