Anti-microbial surfaces by plasma assisted immobilization of chitosan.

This report presents the methods and processes involved in the development of an anti-microbial coating of quaternized chitosan on a glass surface. The antimicrobial effect of the quaternized chitosan was tested against a variety of bacteria such as Escherichia coli, Staphylococcus aureus and Pse...

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Main Author: Toh, Daniel Seng Wei.
Other Authors: Chan Bee Eng, Mary
Format: Final Year Project
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/39565
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-395652023-03-03T15:40:36Z Anti-microbial surfaces by plasma assisted immobilization of chitosan. Toh, Daniel Seng Wei. Chan Bee Eng, Mary School of Chemical and Biomedical Engineering Li Peng DRNTU::Engineering::Materials::Plasma treatment DRNTU::Engineering::Chemical engineering::Biotechnological production This report presents the methods and processes involved in the development of an anti-microbial coating of quaternized chitosan on a glass surface. The antimicrobial effect of the quaternized chitosan was tested against a variety of bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa as well as fungi such as Candida albicans and Fusarium solani to verify its anti-microbial property against micro-organisms. The anti-microbial coating was applied by two step plasma treatment (TSPT) using Argon plasma to immobilize quaternized chitosan on the glass surface. The anti-microbial property of the coating was tested against bacterial Escherichia coli and the results showed that the quaternized chitosan immobilized surface was capable of killing the bacteria. Using design of experiments technique, the effects of power and time duration of each of the 2 steps of the plasma treatment process was investigated. It was determined that power used in the second step and time duration of the first step was significant. In addition, there was a significant interaction between the power used in the first step and time duration of the second step. The plasma treated surface was also examined by contact angle measurement and the surface characterized using atomic force microscopy. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2010-05-31T06:35:54Z 2010-05-31T06:35:54Z 2010 2010 Final Year Project (FYP) http://hdl.handle.net/10356/39565 en Nanyang Technological University 51 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Materials::Plasma treatment
DRNTU::Engineering::Chemical engineering::Biotechnological production
spellingShingle DRNTU::Engineering::Materials::Plasma treatment
DRNTU::Engineering::Chemical engineering::Biotechnological production
Toh, Daniel Seng Wei.
Anti-microbial surfaces by plasma assisted immobilization of chitosan.
description This report presents the methods and processes involved in the development of an anti-microbial coating of quaternized chitosan on a glass surface. The antimicrobial effect of the quaternized chitosan was tested against a variety of bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa as well as fungi such as Candida albicans and Fusarium solani to verify its anti-microbial property against micro-organisms. The anti-microbial coating was applied by two step plasma treatment (TSPT) using Argon plasma to immobilize quaternized chitosan on the glass surface. The anti-microbial property of the coating was tested against bacterial Escherichia coli and the results showed that the quaternized chitosan immobilized surface was capable of killing the bacteria. Using design of experiments technique, the effects of power and time duration of each of the 2 steps of the plasma treatment process was investigated. It was determined that power used in the second step and time duration of the first step was significant. In addition, there was a significant interaction between the power used in the first step and time duration of the second step. The plasma treated surface was also examined by contact angle measurement and the surface characterized using atomic force microscopy.
author2 Chan Bee Eng, Mary
author_facet Chan Bee Eng, Mary
Toh, Daniel Seng Wei.
format Final Year Project
author Toh, Daniel Seng Wei.
author_sort Toh, Daniel Seng Wei.
title Anti-microbial surfaces by plasma assisted immobilization of chitosan.
title_short Anti-microbial surfaces by plasma assisted immobilization of chitosan.
title_full Anti-microbial surfaces by plasma assisted immobilization of chitosan.
title_fullStr Anti-microbial surfaces by plasma assisted immobilization of chitosan.
title_full_unstemmed Anti-microbial surfaces by plasma assisted immobilization of chitosan.
title_sort anti-microbial surfaces by plasma assisted immobilization of chitosan.
publishDate 2010
url http://hdl.handle.net/10356/39565
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