Experimental and theoretical study of matrix-assisted refolding

• المؤلف الرئيسي: Zhang, Chun Yan
• مؤلفون آخرون: Arvind Rajendran
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Engineering::Chemical engineering::Biotechnology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/39800

Inclusion Bodies (IBs), which are dense, insoluble, biologically inactive protein aggregates, are commonly produced in industrial scale protein expression. Matrix-assisted refolding (MAR), or On-Column Refolding (OCR), is a process which transforms IBs from their aggregated form to the correctly fol...