Construction and characterisation of a siclopps cyclic peptide library.

• Main Author: Koh, Ethel Rui Li.
• Other Authors: School of Physical and Mathematical Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/39916
• Institution: Nanyang Technological University

Cyclic peptide libraries are valuable as they are significantly resistant to cellular catabolism, making them useful for manipulation of cellular processes, and their conformational stability allows greater potency in binding to target receptors. SICLOPPs (Split-Intein Circular Ligation of Peptides...