Investigating the role of ras-regulated non-coding RNAs involved in cell growth and transformation.
Oncogenic Ras promotes growth and proliferation in cancer cells but could lead to growth arrest in normal primary cells by inducing the expression of tumour suppressor genes such as p16INK4A and p53. This phenomenon is thought as a mechanism to protect cells from aberrant growth caused by stimulatio...
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Format: | Final Year Project |
Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/10356/39942 |
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Institution: | Nanyang Technological University |
Language: | English |