Developing a method to identify small molecule binding sites on proteins : a case study with ATP.

• Main Author: Li, Kun Quan.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Biomathematics
• Online Access: http://hdl.handle.net/10356/40042
• Institution: Nanyang Technological University

The binding of small molecule ligands onto proteins is a key step in many cellular processes. Depending on the flexibility of ligands and proteins, binding sites can differ in terms of shape and size, allowing different interactions of the protein with ligands of different confirmation. The aim of t...