The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment

Enteric viruses have emerged as important causes of major waterborne disease outbreaks in recent years. The occurrence of enteric viruses in aquatic environments constitutes a major health hazard because of their low infective dose and resistance to environmental breakdown. Currently, our knowledge...

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Main Author: Aw, Tiong Gim
Other Authors: Gin Yew-Hoong, Karina
Format: Theses and Dissertations
Language:English
Published: 2010
Subjects:
Online Access:https://hdl.handle.net/10356/41527
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-415272023-03-03T19:36:49Z The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment Aw, Tiong Gim Gin Yew-Hoong, Karina School of Civil and Environmental Engineering DRNTU::Engineering::Environmental engineering::Water supply Enteric viruses have emerged as important causes of major waterborne disease outbreaks in recent years. The occurrence of enteric viruses in aquatic environments constitutes a major health hazard because of their low infective dose and resistance to environmental breakdown. Currently, our knowledge on the occurrence of enteric viruses in tropical water environments is limited. This thesis describes the first study of the prevalence and molecular characterization of waterborne pathogenic viruses in urban water catchments and community wastewaters in Singapore. Noroviruses were determined to be the most prevalent enteric viruses detected in both wastewater and surface water samples. Molecular characterization revealed the genetic diversity of astroviruses, enteroviruses and noroviruses in water environments. The norovirus strains detected in environmental samples were closely related to the concurrently identified clinical strains in Singapore during gastroenteritis outbreaks between August 2006 to January 2007. Knowledge on the occurrence of human enteric viruses in water environments contributes to the understanding of the mechanisms of viral transmission and the possible role played by water as a vehicle of transmission. Doctor of Philosophy (CEE) 2010-07-16T07:18:29Z 2010-07-16T07:18:29Z 2010 2010 Thesis Aw, T. G. (2010). Occurrence and molecular characterization of enteric viruses in the tropical aquatic environment. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/41527 10.32657/10356/41527 en 224 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Environmental engineering::Water supply
spellingShingle DRNTU::Engineering::Environmental engineering::Water supply
Aw, Tiong Gim
The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
description Enteric viruses have emerged as important causes of major waterborne disease outbreaks in recent years. The occurrence of enteric viruses in aquatic environments constitutes a major health hazard because of their low infective dose and resistance to environmental breakdown. Currently, our knowledge on the occurrence of enteric viruses in tropical water environments is limited. This thesis describes the first study of the prevalence and molecular characterization of waterborne pathogenic viruses in urban water catchments and community wastewaters in Singapore. Noroviruses were determined to be the most prevalent enteric viruses detected in both wastewater and surface water samples. Molecular characterization revealed the genetic diversity of astroviruses, enteroviruses and noroviruses in water environments. The norovirus strains detected in environmental samples were closely related to the concurrently identified clinical strains in Singapore during gastroenteritis outbreaks between August 2006 to January 2007. Knowledge on the occurrence of human enteric viruses in water environments contributes to the understanding of the mechanisms of viral transmission and the possible role played by water as a vehicle of transmission.
author2 Gin Yew-Hoong, Karina
author_facet Gin Yew-Hoong, Karina
Aw, Tiong Gim
format Theses and Dissertations
author Aw, Tiong Gim
author_sort Aw, Tiong Gim
title The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
title_short The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
title_full The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
title_fullStr The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
title_full_unstemmed The occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
title_sort occurrence and molecular characterization of enteric viruses in the tropical aquatic environment
publishDate 2010
url https://hdl.handle.net/10356/41527
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