Understanding the response heterogeneity of different cancer cell types toward anti-mitotic drugs II – Vinblastine

• Main Author: Xiao, Li Ming
• Other Authors: Li Hoi Yeung
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Drug Resistance
• Online Access: http://hdl.handle.net/10356/41756
• Institution: Nanyang Technological University

Vinblastine is a microtubule-destabilizing agent used in cancer chemotherapeutic treatment. It acts by binding to microtubules and promoting the depolymerization of microtubules. As a main component of mitotic spindles, microtubules play an important role in mitosis. The action of vinblastine on mic...