Studies of interactions of sphingolipid-interacting peptides and liposomes with surface plasmon resonance.

• Main Author: Chiew, Geraldine Giap Ying.
• Other Authors: Susana Geifman Shochat
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/41822
• Institution: Nanyang Technological University

Special micro domains on cell membranes, known as lipid rafts, contain a high content of sphingolipid and cholesterol. They are preferential sites for the binding of peptides or proteins such as toxins and Amyloid Beta (Aβ) in order to gain entry into the cell. Interactions between these lipid rafts...