Human papillomavirus type 18 E2 protein and its effects on differentiation and cell cycle in keratinocytes.

• المؤلف الرئيسي: Goh, Belinda Jun Yi.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Virology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/41858
• المؤسسة: Nanyang Technological University

High-risk human papillomaviruses (HPVs) are the main etiological agents of cervical cancer. Critical for malignant transformation is the manifestation of the viral E6 and E7 oncogenes, which is associated with viral genome integration and the loss of E2 open reading frame (ORF). The E2 protein is a...