Solution structure of the DNA-binding domain of a human papillomavirus E2 protein : evidence for flexible DNA-binding regions

• Main Authors: Fesik, Stephen W., Egan, David A., Holzman, Thomas F., Petros, Andrew M., Meadows, Robert P., Liang, Heng, Yoon, Ho Sup, Walter, Karl, Robins, Terry
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: https://hdl.handle.net/10356/94176; http://hdl.handle.net/10220/7478
• Institution: Nanyang Technological University

The three-dimensional structure of the DNA-binding domain of the E2 protein from human papillomavirus-31 was determined by using multidimensional heteronuclear nuclear magnetic resonance (NMR) spectroscopy. A total of 1429 NMR-derived distance and dihedral angle restraints were obtained for each of...