A conserved mechanism for binding of p53 DNA-Binding domain and Anti-Apoptotic Bcl-2 family proteins
The molecular interaction between tumor suppressor p53 and the anti-apoptotic Bcl-2 family proteins plays an essential role in the transcription-independent apoptotic pathway of p53. In this study, we investigated the binding of p53 DNA-binding domain (p53DBD) with the anti-apoptotic Bcl-2 family pr...
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Main Authors: | , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/87108 http://hdl.handle.net/10220/46692 |
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Institution: | Nanyang Technological University |
Language: | English |