Crystal structure of the FK506 binding domain of plasmodium falciparum FKBP35 in complex with FK506

The emergence of multi-drug-resistant strains of Plasmodium parasites has prompted the search for alternative therapeutic strategies for combating malaria. One possible strategy is to exploit existing drugs as lead compounds. FK506 is currently used in the clinic for preventing transplant rejection....

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Bibliographic Details
Main Authors: Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/93954
http://hdl.handle.net/10220/7482
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Institution: Nanyang Technological University
Language: English