Optical tweezers assisted surface plasmon resonance imaging of biological cells at nm resolution

• Main Author: Yuan, Larry Xiao Cong.
• Other Authors: School of Electrical and Electronic Engineering
• Format: Research Report
• Language: English
• Published: 2010
• Subjects: DRNTU::Engineering::Electrical and electronic engineering
• Online Access: http://hdl.handle.net/10356/41872
• Institution: Nanyang Technological University

Surface plasmon resonance imaging (SPRi) is an emerging optical technique for imaging low contrast samples at nm resolution. Since the vertical resolution of the surface plasmons extends from sub-nanometer to hundreds of nanometers, SPRi is potentially useful for the real-time monitoring of transport processes, trafficking processes and surface interactions of cell membranes and tissues. The understanding of cell biology is gaining huge global interests as biologists, researchers and doctors attempt to understand cells' proliferation, find treatment for various diseases and monitor intracellular trafficking, to mention a few.