2-AZA-[3,3]-Sigmatropic rearrangement and AZA-PRINS cyclization and their applications in total synthesis of (-)-indolizidine-209B and (-)-perhydrohistrionicotoxin

• 主要作者: Cheng, Hin Soon
• 其他作者: Loh Teck Peng
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2010
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• 在線閱讀: https://hdl.handle.net/10356/42458

Two novel C-C bond formation methodologies, i.e. 2-AZA-[3,3]-sigmatropic rerrangement and aza-Prins cyclization, were developed for the synthesis of linear homoallylic hydroxylamines and 2,3,6-trisubstituted piperidines respectively. These two nitrogen-containing compounds are useful building block...