Quantifying the possible role of non-specific forces and cell deformability in the elimination of senescent red blood cells

• Main Author: Bjorn Neu.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Research Report
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: http://hdl.handle.net/10356/42753
• Institution: Nanyang Technological University

Human erythrocytes have an in vivo live span of about 120 days during which they undergo several physicochemical changes including a greatly enhanced tendency to form aggregates and a decreased deformability. The aging of RBC has been of interest to basic science and clinical investigators for decad...