Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.

The main objective of this project is to explore methods of high throughput functional genomics to analyze molecular mechanisms associated with the invasion machinery by which the human malaria parasites Plasmodium falciparum invade its host erythrocytes. These mechanisms are highly unique to this o...

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Main Author:	Bozdech, Zbynek.
Other Authors:	School of Biological Sciences
Format:	Research Report
Language:	English
Published:	2011
Subjects:	DRNTU::Science::Biological sciences::Microbiology
Online Access:	http://hdl.handle.net/10356/42829
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-42829
record_format	dspace
spelling	sg-ntu-dr.10356-428292023-02-28T17:58:10Z Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite. Bozdech, Zbynek. School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology The main objective of this project is to explore methods of high throughput functional genomics to analyze molecular mechanisms associated with the invasion machinery by which the human malaria parasites Plasmodium falciparum invade its host erythrocytes. These mechanisms are highly unique to this organism and thus can be explored as new targets for malaria intervention strategies. For these studies we chose the approach of chemical genomics in which we analyze the genome-wide transcriptional responses of the parasite cells to small molecular inhibitors that affect the parasite invasion process. ARC 11/05 2011-01-17T02:52:48Z 2011-01-17T02:52:48Z 2009 2009 Research Report http://hdl.handle.net/10356/42829 en 74 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Science::Biological sciences::Microbiology
spellingShingle	DRNTU::Science::Biological sciences::Microbiology Bozdech, Zbynek. Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
description	The main objective of this project is to explore methods of high throughput functional genomics to analyze molecular mechanisms associated with the invasion machinery by which the human malaria parasites Plasmodium falciparum invade its host erythrocytes. These mechanisms are highly unique to this organism and thus can be explored as new targets for malaria intervention strategies. For these studies we chose the approach of chemical genomics in which we analyze the genome-wide transcriptional responses of the parasite cells to small molecular inhibitors that affect the parasite invasion process.
author2	School of Biological Sciences
author_facet	School of Biological Sciences Bozdech, Zbynek.
format	Research Report
author	Bozdech, Zbynek.
author_sort	Bozdech, Zbynek.
title	Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
title_short	Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
title_full	Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
title_fullStr	Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
title_full_unstemmed	Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
title_sort	functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
publishDate	2011
url	http://hdl.handle.net/10356/42829
_version_	1759852964634165248

Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.

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