Part I: Synthesis of sex pheromone of the pine sawfly, Macrodiprion Nemoralis. Part II: Synthetic studies towards the total synthesis of iriomoteolide-1a

• Main Author: Chin, Yen Jin
• Other Authors: Loh Teck Peng
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• Online Access: https://hdl.handle.net/10356/42900
• Institution: Nanyang Technological University

Conjugate addition of Grignard reagents to α,β-unsaturated esters is one of the most convergent strategies for the construction of C–C bonds. Our group has previously developed a highly efficient CuI-Tol-BINAP-catalyzed asymmetric conjugate using Grignard reagents. The absolute stereochemistry of th...