Studies of surface sciences of protein immobilizations for novel immunosensors

• Main Author: Hu, Weihua
• Other Authors: Li Changming
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Medicine::Biosensors; DRNTU::Science::Chemistry::Physical chemistry::Surface chemistry
• Online Access: https://hdl.handle.net/10356/43311
• Institution: Nanyang Technological University

Immunosensors have sparked extensive research interest in recent years due to the urgent demand for reliable, rapid, sensitive, and specific detection of biological species in various areas. In this PhD project several novel nanomaterials including a conducting polymer film of PPy/PPa, a copolymer brush of POEGMA-co-GMA, randomly oriented ZnO nanorods, and self-assembled MWCNTs film, were synthesized and/or functionalized as supporting matrices for immunosensing application. Immunosensors were constructed based on these materials and their performances were evaluated, respectively. Surface sciences of protein immobilization on these materials were investigated to acquire important theoretical and practical knowledge that can be applied to the development of advanced immunosensing devices.