The functional importance of the interaction between p53 and HEXIM1.

Tumor suppressor p53 is an important cell cycle checkpoint protein, regulating cell cycle arrest and apoptotic response. Suppression of p53 functions account for 50% of human tumors. Thus, re-activation of p53 provides an attractive therapeutic target in cancer therapy. Positive transcription elonga...

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Bibliographic Details
Main Author: Chia, Yi Ling.
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/44231
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Institution: Nanyang Technological University
Language: English