The functional importance of the interaction between p53 and HEXIM1.
Tumor suppressor p53 is an important cell cycle checkpoint protein, regulating cell cycle arrest and apoptotic response. Suppression of p53 functions account for 50% of human tumors. Thus, re-activation of p53 provides an attractive therapeutic target in cancer therapy. Positive transcription elonga...
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Format: | Final Year Project |
Language: | English |
Published: |
2011
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Online Access: | http://hdl.handle.net/10356/44231 |
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Institution: | Nanyang Technological University |
Language: | English |