Actinomycin D induces non-random apoptotic DNA breakpoints in human leukemia HL-60 cells.
Apoptosis is a programmed cell death that is induced by prolonged cellular stress. During apoptosis, caspase-activated DNase cleaves DNA at the internucleosomal regions to produce an “apoptotic ladder” that consists of multiples of 180-200bp. We postulate that these apoptotic DNA breakpoints are non...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2011
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| Online Access: | http://hdl.handle.net/10356/44275 |
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| Institution: | Nanyang Technological University |
| Language: | English |