Actinomycin D induces non-random apoptotic DNA breakpoints in human leukemia HL-60 cells.

• المؤلف الرئيسي: Lin, Lifang.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2011
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/44275

Apoptosis is a programmed cell death that is induced by prolonged cellular stress. During apoptosis, caspase-activated DNase cleaves DNA at the internucleosomal regions to produce an “apoptotic ladder” that consists of multiples of 180-200bp. We postulate that these apoptotic DNA breakpoints are non...