Study of sFRP1 and β-catenin of Wnt signaling pathway in triple negative breast cancer and their correlation with clinicopathologic outcomes.

• Main Author: Seah, Cindy Chiou Peng.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/44277
• Institution: Nanyang Technological University

In breast cancer, the correlation of the activation of wnt signaling pathway with clinical outcome and the means resulting in its stimulation have remained as controversial issues. Moreover, triple negative breast cancer (TNBC) tends to have a poorer prognosis. A cohort of 109 representative TNBC ca...