Structural and functional characterization of integrin αLβ2

Integrins are adhesion molecules that transmit bidirectional signals across the plasma membrane by undergoing extensive structural changes. The focus of this thesis is the leukocyte-restricted integrin αLβ2 (Leukocyte-function associated antigen -1, LFA-1; CD11a/CD18). The first part of this thesis...

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Bibliographic Details
Main Author: Tang, Xiaoyan
Other Authors: Tan Suet Mien
Format: Theses and Dissertations
Language:English
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10356/44576
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Institution: Nanyang Technological University
Language: English